Headaches - Aspirin
A version of aspirin has been treating humans for over 2,500 years. Hippocrates was a renowned Greek doctor that was using a form of aspirin in 5th century B.C. Hippocrates treated fever with an extract from willow tree bark. Salacin is the primary chemical and once in the body it is transformed into salicylic acid.
At the end of the 19th century the German company, Bayer, began marketing a modified manufactured form, acetylsalicylic acid (otherwise known as aspirin), devised by chemist Felix Hoffman. The product turned out to be one of the most successful drugs in the history of the world.
For such a simple molecule it has some of the most amazing properties in the biochemical world.
Aspirin has few side effects at the proper dosage and is used to treat dozens of conditions, such as inflammation, heart disease, fever and - of course - headaches. How it does this is in one way well understood, in another way quite a mystery. It is known that when injury occurs to tissue, prostaglandins are released that generate signals down nerve cells to the brain. What happens then is less clear.
Prostaglandins not only contribute to the pain signal, but to the swelling that follows. But how exactly those conditions translate into something we perceive as pain is still a matter of leading edge research. What is 'injured' in the case of a headache is not known.
For decades it was believed that tension headaches, for example, were the result of muscle tension typically in the neck, back or face, hence the name. But contemporary research sees that as less likely. What's more likely, according to the evidence, is that muscle tension is involved but the interaction of serotonin (a neurotransmitter) with nerve cells is more important.
Whatever the ultimate cause, aspirin works by suppressing the cells from making prostaglandins. It interferes with a enzyme (known by the acronym COX) needed to make them, by binding with it. Eventually the combination is filtered out by the kidneys and more aspirin is needed to continue the process.
One possible side effect is that aspirin may do its job too well and remove needed prostaglandins from the stomach, making the lining too thin and leading to stomach upset or even ulcers. Aspirin also interferes with the creation of blood clots (prostaglandins play a part there, too). That can be helpful when used to prevent heart attacks, but is not helpful when you receive a cut or get a bloody nose.
While generally safe, it is possible to overdose on aspirin. The effects are not the same as overdose from other drugs, but in large doses it can interrupt proper kidney function, for example. To combat these effects, drug companies have designed alternatives, such as ibuprofen, acetaminophen and naproxen.
Aspirin is a very valuable component in treating headaches. With the undisputable clinical evidence, aspirin is safe and effective at treating headaches. There are nearly 80 billion aspirin pills taken each year. When taken correctly by patients who are not sensitive to adverse side effects, aspirin is a good tool in treating headaches.
If taken in liquid form, use a carefully calibrated measuring spoon or small cup, rather than a teaspoon.
Chapter 3- When Two Worlds Collide Jobrosmance 1
Hope you enjoy!!! = ----------------------------------- Alexis-OMG!?!?!?!?
Lianna & Melody-What?..... oh WOW that's an awesome looking bus!!!!! or Buses!!
Demi- Wow your guys bus is cooler than mine...... hahaha almost
Mrs.Gray- So do you guys like it?? cause you better your gonna be spending half you lives on this bus!!!
Gray Sisters- YES!!!!!!!!!!!!!!
Melody- Well yeh it's awesome.... I CALL TOP BUNK!!!
*runs inside the bus and finds the bunks and jumps on top of the very top bunk*
Sean- I call the bottom bunk under Melody.
*and runs after her, and Lianna, Alexis, and Demi run after them too*
---------------------
After there first show in New York. (A.N i know i fast forwarded a lot and it's going to skip basically the whole tour too.)
Melody- OMG that was awesome!! The rush, the fans the flashing lights on cameras i mean seriously it's like a light show!!!!!!!!!
Demi- Yeh It's amazing on the first night but you get used to it. =
Lianna- Yeh we better i have the hugest headache OF hugest headaches!!! -----------------------(A.N see fast forwarding right now!!) LAST SHOW of the tour!!!!!!!
EVERYONE- ahhhhhhhh
Melody- I can't believe it's the last show of the tour!!!! I mean it went by too fast.
Demi- I know we have to keep in touch. Oh and i have some friends coming to the after party i would love for you to meet them.
Alexis- Really? Who?
Demi- Um..... you'll see
*Feeling a little AWKWARD!!! (Hint Hint)*
------------------- Right B4 the After Party!!
*Door bell of hotel room rings*
Demi- HEY guys glad you could make it!!
???- Yeh we wouldn't miss one of our best friends "last concert of the tour AFTER PARTY!!!"
Demi- Thanks KEVIN!
Lianna- Hey Demi who is it????
*Comes to the door*
Lianna- Oh Hi, Kevin right?
Kevin- Oh hi you must be Lianna, this is Joe & Nick.
Lianna- Nice to meet you. here I'll get my sisters.
*Lianna Yells For Alexis and Melody*
Lianna- ALEXIS!!!!! MELODY!!! COME TO THE DOOR!!!!
*Melody Comes running*
Melody- OK WHERE'S THE FIRE!!! STOP, DROP & ROLL EVERYBODY!!!
*Melody about to drop and roll*
Lianna- NO stupid, we have company.
Melody- Oh, wow that's embarassing. Oh gosh Hi, Omg it's the Jonas Brothers, I'm a huge fan! It's really great to meet you guys.
*Nick & Melody are about to shake hands when Alexis, running to see what happened, runs into Melody and Melody Smashes into Nick*
Alexis- Omg sorry!
Melody-mhmmmmmmm..... o sorry nick and thanks for breaking my fall. haha just kidding here....
*Helps him up*
---------------------
I know not a great ending but yeh next chapter tomorrow probably after school. gosh my mom is like what are you writing about and she's like I'll ground you if you don't tell me and i'm like why do you have to know!!! haha lol anyway next chapter soon!!
Author: SweetPea172ox
Keywords: short film web series jonsd brothers gray sisters
Added: September 23, 2008
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Author: DIGITALMOTIONXRAY
Keywords: radiological findings x-ray fracture compression facet joint interspinous transverse ligament Tension headache pain
Added: September 24, 2008
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Author: svenaldingerifuqo
Keywords: health
Added: September 21, 2008
Some preservatives, such as monosodium glutamate, can produce headache pain. Hit your thumb with a hammer and the swelling starts. The term 'aura', in this case has nothing to do with alleged fields around the body, but is a cluster of pre-cursor symptoms, such as seeing light flashes. They prevent blood vessels from dilating, thought to be one factor in migraines.
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