Blood is that fragile scarlet tree we carry within us. Osbert Sitwell
Headaches - Preventive Medications
While treating a headache can be effective in dealing with headaches, prevention is an even better approach. It is much more desirable to prevent the headache than to treat the resulting pain. People who get migraines should especially be careful since the pain of migraines is so intense and disruptive to daily activities.
To attack that problem, so-called prophylactic drugs are often recommended as part of a spectrum of treatments. The term may be familiar to those who have used condoms. The meaning is similar. They're used to prevent a certain result, in this case headache pain, before it occurs rather than treating it afterwards. The latter type are termed 'abortive', and have a similar meaning to the common one - they eliminate or counteract an effect after it has happened.
In some cases that prevention may take the form of lifestyle adjustments. Alcohol, particularly red wine, can be a trigger for some migraine sufferers. Excessive activity, even something as mild as walking up steps, does it for others. Lack of sleep, stress, missing meals... the list is long. Adjusting behavior, even though requiring willpower, is often the easiest and safest way to prevent a headache before it strikes.
But for many, drugs are the best answer.
Preventive medicines come in a variety of classes, such as beta-blockers, channel-blockers and others. Sometimes they're combined with or used for drugs to treat other conditions, but have the 'side-effect' of treating headaches or migraines.
Beta-blockers, for example, are used to treat heart conditions, but they are also often effective in preventing migraines. They prevent blood vessels from dilating, thought to be one factor in migraines. Since they also help treat cardiac or chest pain (angina) and high blood pressure, in some cases they will work to relieve triggers for migraine.
Channel-blockers are another kind of heart pill that is also used as migraine prevention. Typically in the form of so-called CCBs (Calcium Channel Blockers), they work by reducing or blocking calcium from entering heart muscle cells. Calcium is essential in the biochemistry that allows the heart to function, but too much can be a problem. Since they reduce heart action, they sometimes have the side-effect of reducing the odds of migraine.
Some anti-depressant medications can be useful in treating headaches and migraine, since depression is one of the possible triggers of an attack. Prevent one cause, and the odds of the effect are reduced. Amitriptyline and doxepin are two common drugs of this type, and they have a painkilling effect as well at low doses.
Anti-seizure medications are sometimes used as part of a preventive strategy. Migraines and seizures have some similar neurological features. One such is a condition afflicting about 20% of migraine sufferers - auras or prodromes. These are a set of symptoms, such as flashes of light or loss of vision, that are precursors to a migraine episode.
Anti-serotonin medications are another possible treatment. Contemporary research suggests that serotonin (a neurotransmitter in the brain) plays an important role in migraines. Using a compound that can substitute in nerve cell receptors for serotonin, while having a slightly different structure, can prevent an attack.
There is not one single medicine that is accepted as the right preventative treatment of headaches. You should always check with your doctor when considering taking a new drug. Ask your doctor for an evaluation and advice on all treatment possibilities.
Blood in vomit or stools, general stomach upset even dizziness are commonly reported.
Medtronic Announces First Clinical Data On Occipital Nerve Stimulation For Chronic Migraine
Medtronic, Inc. (NYSE: MDT) announced that data from a multicenter, prospective, randomized, singleblinded, Controlled investigational study using its neurostimulation system to stimulate the occipital nerves as a potential approach to treating medically refractory chronic migraines will be presented during a late-breaking session at the annual scientific meeting of the American Headache Society (AHS) tomorrow in Boston.
Data On Highly Effective Migraine Treatment Presented By OptiNose
OptiNose has announced that it presented important new data demonstrating the superior performance of its novel nasal drug delivery device with sumatriptan for the treatment of migraines. The Phase II results indicate that the drug-device combination achieves migraine relief as quickly and efficiently as injections without the discomfort, inconvenience and risk of needle-stick injuries. OptiNose presented the data at the Annual Scientific Meeting of the American Headache Society in Boston.
Phase II Results Of COL-144 Presented At European Headache And Migraine Trust International Congress 2008
CoLucid Pharmaceuticals, Inc., an innovative biotechnology company focusing on therapies for central nervous system disorders, announced Phase II results of its lead compound COL-144 in the treatment of acute migraine. Results demonstrated that COL-144 was safe and effective in relieving migraine headaches. COL-144 is a first-in-class Neurally Acting Anti- Migraine Agent (NAAMA), which unlike triptans, exhibits anti-migraine activity without causing vasoconstriction.
Good posture helps keep muscles from tensing at the wrong time and in the wrong ways. For many years it was suspected they were the result of dilation of blood vessels, but contemporary research leans to other explanations. Migraines have a strong tendency to run in families, while 40% of those with tension headaches share a family history with sufferers. Are there types of people that are at a greater risk of getting headaches? The term 'aura', in this case has nothing to do with alleged fields around the body, but is a cluster of pre-cursor symptoms, such as seeing light flashes. How it does this is in one way well understood, in another way quite a mystery.
|
